Systematic Review of the Risk of Permanent Alopecia with Docetaxel Treatment for Breast Cancer

The review aimed to assess the risk of permanent alopecia associated with docetaxel treatment in breast cancer patients. A literature search identified three relevant studies. One case reported by Tallon et al. described a 72-year-old woman who experienced persistent scalp hair loss 13 months after completing a regimen including docetaxel, with minimal regrowth and a biopsy showing reduced hair follicles. This case highlighted the potential for docetaxel to cause permanent alopecia, although the overall incidence remained unclear due to limited data.