Preparatory Work to Support the Risk Assessment for Peri- and Postmenopausal Women Taking Food Supplements Containing Isolated Isoflavones

October 2015 in “ EFSA supporting publications ”

Marja Tijhuis, Esmée L. Doets, Vera van der Velpen, Marije Vonk Noordegraaf‐Schouten

isoflavones food supplements peri-menopausal postmenopausal hormones

TLDR Isoflavones may help with menopause symptoms but could be risky for women with hormone-sensitive cancers.

The document detailed preparatory work for assessing the risks associated with peri- and postmenopausal women taking food supplements containing isolated isoflavones. Conducted by researchers from Pallas Health Research and Consultancy and Wageningen University, the study was commissioned by the European Food Safety Authority. The report aimed to ensure transparency and was not an official output of the Authority. The findings contributed to understanding the safety and potential health impacts of isoflavone supplements in the specified demographic.

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research Scientific Opinion on the Substantiation of Health Claims Related to Soy Isoflavones and Protection of DNA, Proteins, and Lipids from Oxidative Damage, Maintenance of Normal Blood LDL Cholesterol Concentrations, Reduction of Vasomotor Symptoms Associated with Menopause, Maintenance of Normal Skin Tonicity, Contribution to Normal Hair Growth, and Cardiovascular Health

22 citations, July 2011 in “EFSA journal”

There is not enough evidence to support health claims about soy isoflavones.

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research Preparatory Work to Support the Risk Assessment for Peri- and Postmenopausal Women Taking Food Supplements Containing Isolated Isoflavones

3 citations, October 2015 in “EFSA supporting publications”

Isoflavones may help with menopause symptoms but could be risky for women with hormone-sensitive cancers.