TLDR Platelet-rich plasma can speed up bone healing and shows promise in orthopaedic treatments.
This review explores the role of platelet-rich plasma (PRP) in accelerating bone healing, highlighting its regenerative potential due to its rich composition of platelets and growth factors. PRP's mechanisms include releasing growth factors, chemotaxis, and angiogenesis, which contribute to its effectiveness in fracture healing and orthopaedic surgeries. The review emphasizes the promising outcomes of clinical trials, while also addressing safety considerations, patient selection, and the need for standardisation in PRP preparation and application. Future prospects for PRP in bone healing include precision medicine, integration with emerging therapies, and expanded applications, particularly in orthopaedics and regenerative medicine.
2 citations
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November 2023 in “Curēus” Platelet-rich plasma (PRP) speeds up skin wound healing and has potential in medical and cosmetic uses.
21 citations
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February 2023 in “Bioengineering” Standardizing PRP therapy practices and regulations in Europe is crucial for safe and effective treatment.
12 citations
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December 2020 in “Frontiers in Cell and Developmental Biology” The review found that the way Platelet-Rich Plasma is made varies a lot, which can change the results of medical treatments.
848 citations
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October 2020 in “International Journal of Molecular Sciences” PRP shows promise in treating joint and spine issues, but translating lab results to humans is challenging.
87 citations
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February 2019 in “Tissue Engineering Part B Reviews” Platelet-rich plasma can effectively treat and prevent tissue infections.
19 citations
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January 2017 in “International Journal of Trichology” The document concludes that injecting platelet-rich plasma can effectively treat androgenetic alopecia, a type of hair loss.
24 citations
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November 2017 in “Aesthetic Plastic Surgery” All types of Platelet-Rich Plasma (PRP) can treat hair loss, but homologous PRP works best due to its higher platelet count and growth factors from multiple donors.
