Promises And Pitfalls Of Regenerative Therapies For Androgenetic Alopecia: Platelet-Rich Plasma, Photobiomodulation, Stem Cells, And Exosomes

January 2025 in “ Open Science Framework ”

Wang Tong, Gupta, Aditya

androgenetic alopecia platelet-rich plasma photobiomodulation stem cells exosomes PRP

TLDR Current evidence is insufficient to fully endorse regenerative therapies for hair loss.

This review explores the potential and challenges of regenerative therapies for androgenetic alopecia (AGA), focusing on platelet-rich plasma (PRP), photobiomodulation (PBM), stem cells, and exosomes. AGA is a common hair loss condition affecting a significant portion of the population. PRP and PBM are already used in clinical settings, while stem cells and exosomes are still under investigation due to regulatory and safety concerns. The review systematically analyzes clinical evidence from the past 5 years, examining the mechanisms, efficacy, and safety of these treatments. The findings suggest that regenerative therapies may offer promising results in improving hair density and thickness, although more high-quality empirical evidence is needed to establish standardized treatment protocols.

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community Microneedling versus Platelet-Rich Plasma

in Research/Science 9 upvotes 3 months ago

Microneedling and Platelet-Rich Plasma (PRP) are equally effective for treating androgenetic alopecia, with no additional benefits from PRP over microneedling. Both treatments are safe and well-tolerated.

community Treatment of Androgenetic Alopecia: Current Guidance and Unmet Needs

in Research/Science 3 upvotes 2 years ago

The review discusses traditional hair loss treatments like minoxidil and finasteride, and newer options like Low-Level Laser Therapy, microneedling, and platelet-rich plasma for androgenetic alopecia. It highlights the need for more high-quality trials to assess these treatments' effectiveness and standardized protocols for emerging therapies.

community Evidenced Based Meta-Analyses and Systemic Reviews of Androgenic Alopecia and Treatments

in Research/Science 15 upvotes 5 years ago

Evidence-based treatments for androgenic alopecia, such as minoxidil, finasteride, low-level laser light therapy, dutasteride, platelet-rich plasma, and topical ketoconazole. It discusses the efficacy, safety, and mechanism of action of these treatments, as well as future developments in understanding this polygenic condition.

community Most Recent Interesting Hairloss Studies: 10% Minox vs 5% Minox / Radio Rrequency Treatment for AA / Topical Ketoconazole / PRP+Minox vs Minox vs PRP / Alopecia as a systemic disease

in Treatment 85 upvotes 6 years ago

Treatments for hair loss, such as topical minoxidil, platelet-rich plasma therapy with or without minoxidil, ketoconazole, non-abative radio frequency, natural products, finasteride and cortexolone 17 alpha propionate. The post evaluates the efficacy and safety of these treatments in various studies.

community I have successfully stopped my hormone-induced hair loss ( caused by PCOS,) for 2 years now but I can't seem to be able to regrow the lost hair. Has anyone tried Platelet-Rich Plasma Therapy (PRP)?

in Female 7 upvotes 4 years ago

GentleIris stopped hormone-induced hair loss with diet changes but couldn't regrow lost hair. A reply suggested microneedling instead of Platelet-Rich Plasma Therapy (PRP) for hair regrowth.

community I have been on finasteride for 9 months. (6 months on 0.25 mg, 3 months into 0.5 mg daily) here are the progress pictures.

in Progress Pictures 273 upvotes 7 months ago

A user shared progress pictures after 9 months on finasteride, starting with 0.25 mg and increasing to 0.5 mg daily, noting improved hair density, especially at the crown, with initial side effects that resolved after the first month. The discussion includes user experiences with finasteride, concerns about side effects, and alternative treatments like rosemary oil and platelet-rich plasma therapy.

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