Possible Reasons for Urethral PSA Variations After Radical Prostatectomy

    January 2010 in “ Acta Chirurgica Iugoslavica ”
    T. Pejcic, Jovan Hadzi-Djokic, Biljana Marković, N. Lalic, B. Glisic
    Image of study
    TLDR Higher urethral PSA levels after prostate removal may be linked to more scalp hair loss and more PSA in urethral glands.
    The study, conducted 13 years ago, examined the reasons for variations in urethral prostate specific antigen (urPSA) levels in 46 patients who had undergone radical prostatectomy. The average urPSA was found to be 20.9+47.5 ng/ml. Patients were divided into two groups based on a urPSA cut-off of 2.0 ng/ml: Group A (urPSA < 2.0 ng/ml) and Group B (urPSA = 2.0 ng/ml). The study found that patients in Group A had significantly lower average androgenic alopecia (AGA) scores and lower postoperative PSA levels than those in Group B. The conclusion was that patients with higher urPSA levels also had higher AGA scores and higher postoperative PSA levels, likely due to increased local dihydrotestosterone activity in the scalp and PSA-secreting urethral glands.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 8 results

      community Fresh off the press: Dutasteride may cause chronic infertility

      in Research/Science  640 upvotes 3 months ago
      Dutasteride may cause chronic infertility by reducing semen volume and motility, with concerns about irreversible prostate fibrosis. Users consider switching to finasteride or using treatments like minoxidil and microneedling, weighing hair preservation against fertility.

      community Finasteride - discomfort pelvir/urethra

      in Finasteride  79 upvotes 1 month ago
      Finasteride can cause pelvic or urethral discomfort for some users. Reducing the dose to 0.25 mg on Mondays, Wednesdays, and Fridays is being considered as a potential solution.

      community fin + min progress: month 1 vs month 6

      in Progress Pictures  452 upvotes 2 months ago
      The user shared progress pictures showing hair improvement after using 1mg finasteride daily and 5% minoxidil spray once a day for six months. Other users suggested adding microneedling to enhance results and discussed side effects and product recommendations.

      community Small personal success with fin and microneedling

      in Chat  29 upvotes 4 years ago
      A 29-year-old man experienced significant hair thickening at the front and top after using finasteride and microneedling for two months, as noticed by his hairdresser. He used 0.5 mg/day of finasteride orally, switched to a topical solution, and performed microneedling with a Derminator2 every 6-7 days.

      community What happened to the 40mg dutasteride daily and Cyclosporine dude?

      in Chat  40 upvotes 2 weeks ago
      A user previously claimed to take 40mg of dutasteride daily and planned to try Cyclosporine, but their account and comments have since been deleted, raising concerns about their well-being. Other users discussed the risks and effectiveness of high doses of dutasteride, with some sharing their own experiences using dutasteride, finasteride, and minoxidil for hair loss treatment.

    Similar Research

    5 / 431 results