Case Report: Psoriasiform Eczema with Immune-Mediated Comorbidities Treated with Upadacitinib

This case series examined the effects of upadacitinib on psoriasiform eczema and associated immune-mediated comorbidities in 5 male patients. The treatment was rapidly effective for psoriasiform eczema in all cases. It showed good effectiveness for alopecia areata in 2 patients, partial results for vitiligo in 2 patients, complete remission for ulcerative colitis in 1 patient, and partial improvement for hidradenitis suppurativa in 1 patient. The study concludes that upadacitinib is effective for psoriasiform eczema and some comorbidities, but further research is needed to assess its efficacy for alopecia areata, vitiligo, and hidradenitis suppurativa.