Platelet-Rich Plasma Applications, The Past 5 Years: A Review Article

    Michael G Buontempo, Lina Alhanshali, Jerry Shapiro, Kristen Lo Sicco, Michael Garshick
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    TLDR PRP can reduce pain and improve function, but more standardized research is needed.
    This review article examines the applications and evidence of platelet-rich plasma (PRP) over the past 5 years, focusing on randomised controlled trials. PRP, with a platelet concentration five times greater than baseline, has shown effectiveness in reducing pain and improving functional outcomes in various medical fields, though some studies report no significant differences compared to other treatments or placebo. Key limitations include small sample sizes, short follow-up periods, and inconsistent PRP preparation methods. The article emphasizes the need for standardized reporting to fully establish PRP's effectiveness and optimal use, while also noting its growing market presence.
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