Post-Acute COVID-19 Syndrome and Its Prolonged Effects: An Updated Systematic Review

    Jahanzeb Malik, Zaidi Smj, Raja Muhammad Iqbal, Kanwal Iqbal Khan, Ali M, Rana As, Waqar Au, Uzma Ishaq
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    TLDR Long-lasting COVID-19 symptoms like fatigue and breathing difficulties can persist for over 60 days, requiring ongoing care.
    This systematic review analyzed 21 articles out of 153 to estimate the demographics, clinical characteristics, and prevalence of post-acute COVID-19 symptoms. The study found that even after 60 days of initial infection, patients can still experience symptoms such as fatigue (54.11%), dyspnea (24.38%), alopecia (23.21%), hyperhidrosis (23.6%), insomnia (25.98%), anxiety (17.29%), and arthralgia (16.35%). Additionally, new-onset hypertension, diabetes, neuropsychiatric disorders, and bladder incontinence were reported. The authors concluded that multidisciplinary care and regular follow-up are necessary for patients experiencing these prolonged effects of COVID-19.
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