Phase II Study of Safusidenib Erbumine in Patients with Chemotherapy- and Radiotherapy-Naïve Isocitrate Dehydrogenase 1-Mutated WHO Grade 2 Gliomas

    November 2025 in “ Neuro-Oncology ”
    Yoshiki Arakawa, Ryuta Saito, Yonehiro Kanemura … Hideo Nakamura
    Studysummary In this study, safusidenib erbumine was evaluated for its efficacy and safety in patients with untreated IDH1-mutated WHO grade 2 gliomas, achieving a 44.4% objective response rate and 87.9% 24-month event-free probability, but with some mild to moderate adverse effects.
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