The Effects of Low-Intensity Pulsed Magnetic Field on the Proliferation and Differentiation of Epidermal Stem Cells During Wound Healing Process

January 2006 in “ Zhongguo linchuang jiepouxue zazhi ”

Zhu Hong-xiang

epidermal stem cells wound healing low intensive pulse magnetic fields PEMFs integrin β1 keratin 14

TLDR Low intensive pulse magnetic fields can speed up wound healing by boosting skin stem cell growth and development.

The study investigated the effects of low intensive pulse magnetic fields (PEMFs) on the proliferation and differentiation of epidermal stem cells (ESCs) during wound healing in a rat model with deep second-degree burns. Forty rats were divided into control (10 rats) and experimental groups (30 rats), with the latter exposed to PEMFs at frequencies of 1 Hz, 10 Hz, and 50 Hz. Results showed that the experimental groups had significantly shorter wound healing times and higher expressions of integrin β1 and keratin 14 compared to the control group, with the 50 Hz frequency showing the most significant effects. The study concluded that PEMFs might promote wound healing by enhancing the proliferation and differentiation of ESCs.

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research The Role of Hair Follicle Dermal Sheath Cells in Rat Skin Wound Healing: An Experimental Study

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