A Comparative Study of Pain Perception During Platelet Rich Plasma Therapy Using Sodium Citrate and Acid Citrate Dextrose-A as Anticoagulant

This study investigated pain perception in 30 patients with androgenetic alopecia undergoing platelet rich plasma (PRP) therapy using two different anticoagulants: sodium citrate and acid citrate dextrose-A (ACD-A). Each patient's scalp was treated with PRP using sodium citrate on one half and ACD-A on the other. Results showed that PRP with sodium citrate caused significantly less pain than with ACD-A. The study concludes that the choice of anticoagulant affects pain levels during PRP, with sodium citrate being less painful, but suggests that larger studies are needed to confirm these findings.