Hydrogel Composites for Multifunctional Biomedical Applications

April 2024 in “ Journal of composites science ”

Hossein Omidian, Arnavaz Akhzarmehr, Sankhanilay Roy Chowdhury

hydrogel composites PRP-loaded DECHS hydrogel hair follicle inductive ability hair follicle regeneration blood vessel formation platelet-rich plasma PRP

Studysummary This review details how hydrogel composites play crucial roles in regenerative medicine, tissue engineering, and drug delivery systems, highlighting innovations in these applications and addressing challenges like bioactivity, biomechanical compatibility, and controlled drug release.

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The review article "Hydrogel Composites for Multifunctional Biomedical Applications" highlights the significant role of hydrogel composites in various biomedical fields, including regenerative medicine, tissue engineering, and drug delivery systems. It emphasizes the integration of growth factor delivery systems, innovations in clinical applications, and the challenges of achieving bioactivity and biomechanical compatibility. The study also investigates the effectiveness of PRP-loaded DECHS hydrogel composites in enhancing hair follicle inductive ability in nude mice, showing significant improvements in hair follicle regeneration and blood vessel formation. Additionally, the document discusses various innovative hydrogel composites designed for bone and cartilage regeneration, dental and spinal repair, and drug delivery systems, showcasing their potential to transform biomedical research and clinical practice through multifunctional capabilities and adaptability.

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Research cited in this study

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research Advancements and Applications of Injectable Hydrogel Composites in Biomedical Research and Therapy

2 citations , June 2023 in “Gels”

This study highlights the versatility and potential of injectable hydrogel nanocomposites in biomedical research, emphasizing their roles in controlled drug delivery, tissue regeneration, and treatment of various conditions, such as cardiac issues, joint diseases, and bone regeneration.

research Scalable and High-Throughput Production of an Injectable Platelet-Rich Plasma (PRP)/Cell-Laden Microcarrier/Hydrogel Composite System for Hair Follicle Tissue Engineering

November 2022 in “Journal of Nanobiotechnology”

In this study, researchers used a new method with platelet-rich plasma-loaded microcarriers to enhance dermal papilla cell activity and hair follicle regeneration, achieving significant hair and vessel growth in a mouse model compared to control groups.