Onychomadesis Associated with Childhood Hand-Foot-Mouth Disease

The document presents findings from various studies related to hair and nail conditions. One study discussed hair casts, also known as pseudonits, which are tubular accretions on the hair shaft often misdiagnosed as pediculosis capitis. A case of a 9-year-old girl misdiagnosed with pediculosis capitis was presented, where the correct diagnosis was hair casts, and the treatment with 0.025% retinoic acid and manual removal was effective. Another study with 45 female Korean patients aged 26-55 years investigated the relationship between hair loss and trichodynia, finding increased expression of nerve growth factor (NGF) and neurokinin-1 (NK-1), suggesting their involvement in hair loss associated with trichodynia. A third study reported on the long-term safety and efficacy of LATISSE (bimatoprost 0.03% solution) for treating eyelash hypotrichosis in 368 subjects with idiopathic and post-chemotherapy hypotrichosis, showing that daily application over a year was safe and effective. Lastly, a report on onychomadesis associated with hand-foot-mouth disease (HFMD) in three Chinese children aged 3-13 years old suggested a causal relationship between HFMD and nail matrix arrest, with the incidence of such nail changes possibly being under-reported.