Effect of Obesity on General Health and Parotid Salivary Glands of Rats: Histological and Ultrastructural Study
April 2024
in “
Alexandria Dental Journal
”
New to calcium? There is a guide in the encyclopedia. Read the guide → Studysummary This study found that a high-fat diet in rats led to obesity, insulin resistance, and structural changes in the parotid salivary glands, with associated negative impacts on general health.
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The study investigated the impact of a high-fat diet on the parotid salivary glands of rats, using 24 adult male albino rats divided into two groups. The high-fat diet group showed significant changes, including increased body weight, food and water intake, hair loss, and elevated levels of insulin, cholesterol, glucose, and calcium in blood serum compared to the control group. Histological and ultrastructural analyses revealed a loss in the typical configuration of the salivary glands in the high-fat diet group. The study concluded that a high-fat diet leads to obesity, insulin resistance, decreased general health, and structural damage to the parotid salivary glands.
