Nutritional Dermatoses in Rats

    November 1937 in “ Experimental biology and medicine
    Paul György, M. X. Sullivan, Howard T. Karsner
    TLDR Nutritional deficiencies in rats cause skin problems that can be treated with the right vitamins.
    The document discusses three distinct scaly dermatoses in rats caused by nutritional deficiencies: vitamin H (biotin) deficiency, vitamin B6 deficiency, and lactoflavin (riboflavin) deficiency. Vitamin H deficiency, induced by a diet high in egg-white, leads to symptoms such as seborrheic dermatitis, erythema, intertrigo, generalized scaling, alopecia, and pruritus, which can be cured by administering vitamin H. The condition progresses to generalized exfoliative dermatitis, with microscopic examination revealing edema, acanthosis, and spongiosis in the skin. Proper identification and differentiation of these conditions are crucial to avoid confusion in nutritional research.
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