Novel Collagen Sponge Reinforced with Polyglycolic Acid Fiber Produces Robust, Normal Hair in Murine Hair Reconstitution Model

The study explored a modified hair reconstitution method using a collagen sponge scaffold reinforced with polyglycolic acid (PGA) fiber in a murine model. Traditional methods using silicone chambers faced issues like leakage and inconsistent hair growth. The research found that while conventional collagen sponges disrupted normal hair follicle formation, the PGA fiber-reinforced collagen sponges effectively supported the proper restructuring of skin and hair follicles. This indicated the potential of PGA fiber-containing collagen sponges for improving hair reconstitution in both research and clinical settings.