Neurosteroids Involved in Regulating Inhibition in the Inferior Colliculus

    September 2006 in “ Journal of Neurophysiology ”
    Yuri B. Saalmann, Ian G. Morgan, Mike B. Calford
    Studysummary In this study, researchers found that after reducing GABAergic inhibition in rats' auditory midbrain, the brain quickly compensates by increasing local neurosteroid synthesis to maintain balance in neural circuits.
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    Research cited in this study 2

    1. Stress-Induced Deoxycorticosterone-Derived Neurosteroids Modulate GABA A Receptor Function and Seizure Susceptibility Journal of Neuroscience · 2002
    2. Inhibition of Rat Alpha-Reductases by Finasteride: Evidence for Isozyme Differences in the Mechanism of Inhibition The Journal of Steroid Biochemistry and Molecular Biology · 1997

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