Nanocarriers‐Based Topical Formulations for Acne Treatment

The document discussed the use of nanocarriers in topical formulations for acne treatment, highlighting their advantages over traditional methods. Retinoids, while effective, had side effects, and plant extracts and essential oils faced challenges with skin penetration and stability. Nanocarriers, including polymeric and lipid carriers, offered improved drug release, stability, and reduced side effects. They facilitated deposition into hair follicles and retention in the epidermis/dermis, targeting acne development and clinical forms. Performance assays showed that nanocarrier systems effectively reduced acne lesions, inflammation, and retinoid-induced irritation, while being safe and non-irritant to the skin. The chapter reviewed recent advancements in nanocarrier-based antiacne therapy.