Multicolor Cell Barcoding Technology for Long-Term Surveillance of Epithelial Regeneration in Zebrafish

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Epithelial stem cells can adapt and help in tissue repair and regeneration.

Hair regeneration needs dynamic cell behavior and mesenchyme presence for stem cell activation.

Skin stem cells are crucial for maintaining and repairing the skin and hair, using a complex mix of signals to do so.