Mucocutaneous Manifestations of Acquired Hypoparathyroidism: An Observational Study

    January 2012 in “ Indian Journal of Endocrinology and Metabolism ”
    Kapildev Das, Somenath Sarkar, Modhuchanda Mondal, Arpit Shrimal
    TLDR Most patients with acquired hypoparathyroidism after neck surgery had hair, nail, and skin issues.
    This observational study, conducted from 2006 to 2011, examined the mucocutaneous manifestations of acquired hypoparathyroidism in 21 patients, primarily following thyroid or parathyroid surgery. The study found that 76.19% of patients exhibited mucocutaneous symptoms, with the most common being loss of axillary hair (61.90%), loss of pubic hair (52.38%), and coarsening of body hair (47.62%). Nail changes were also prevalent, with brittle and ridged nails observed in 38.09% of patients. Skin manifestations included dry skin in 52.38% of patients, and less commonly, pustular psoriasis and acne form eruptions. The study highlighted a higher incidence of hair-related issues compared to previous literature and identified new skin problems such as complete nail loss and alopecia areata post-surgery.
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