13 citations
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April 2009 in “Acta Medica Scandinavica” This study found that minoxidil effectively reduced blood pressure in patients with severe hypertension and renal failure resistant to conventional drugs, though side effects like hirsutism and edema were common.
18 citations
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January 1976 in “Clinical Science” This study found that minoxidil significantly reduced supine diastolic pressure in 94% of patients with severe essential hypertension within 4 weeks, but some patients experienced side effects such as increased hair growth and fatigue.
November 2024 in “International Society of Hair Restoration Surgery” This study investigated adverse events from low-dose systemic minoxidil in an older population with hair loss and found that 19% experienced mainly facial and body hypertrichosis, managed with interventions like dose reduction and diuretics; no serious adverse events occurred.
16 citations
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March 1981 in “PubMed” This study found that minoxidil significantly reduced blood pressure in patients with intractable hypertension and was generally well-tolerated, although fluid retention and hirsutism posed some challenges.
5 citations
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February 1996 in “Clinical pharmacology and therapeutics/Clinical pharmacology & therapeutics” Minoxidil given intravenously caused small changes in diastolic blood pressure and increased heart rate at higher concentrations in patients with high blood pressure.