Minoxidil in Androgenic Alopecia: New Formulations with Improved Delivery

    Alaa Al-Taie, Myasar Alkotaji, Hani M Almukhtar
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    Studysummary In this review, researchers examined the molecular pharmacology and effects of topical minoxidil, noting its potential to treat androgenetic alopecia by enhancing hair regrowth, while also discussing advanced formulation methods like nanoemulsion and nanocarrier systems to improve its delivery.
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    The review paper discusses the use of Minoxidil, originally a hypotensive agent, for the treatment of hair loss due to its hypertrichosis (excessive hair growth) side effect. The exact mechanism of Minoxidil's action on hair follicles is still unclear. However, it is considered an effective treatment for reducing hair loss and promoting regrowth in conditions like androgenetic alopecia. The paper also highlights innovations in the formulation of topical Minoxidil to enhance its delivery. This includes the use of nanoemulsion and nanocarrier systems such as nanoparticles and liposomes, which have improved the topical delivery of the drug.
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