Methotrexate for Generalized Pustular Psoriasis in a 2-Year-Old Child

January 2005 in “ Pediatric Dermatology ”

Sunil Dogra, Muthu Sendhil Kumaran, Sanjeev Handa, Amrinder J. Kanwar

methotrexate generalized pustular psoriasis GPP hypopigmented mycosis fungoides UVA1 treatment alopecia areata autoimmune genetic predisposition geographic tongue nonpustular psoriasis Fox Fordyce disease adapalene gel UVA1 adapalene

TLDR Methotrexate effectively treated a 2-year-old's generalized pustular psoriasis without side effects.

The document discussed several dermatological conditions in children, including a 2-year-old boy with generalized pustular psoriasis (GPP) successfully treated with methotrexate, which led to a remarkable clearance of pustules and resolution of toxic symptoms without side effects. It also covered a 9-year-old girl with hypopigmented mycosis fungoides who achieved complete remission after UVA1 treatment, a rare case of alopecia areata in a 5-month-old infant highlighting its autoimmune nature and genetic predisposition, and geographic tongue in children with nonpustular psoriasis suggesting a potential link between the two conditions. Additionally, it described a rare case of Fox Fordyce disease in a 10-year-old girl, treated with 0.1% adapalene gel, noting the condition might be underdiagnosed in prepubertal girls.

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