Influences of Different Mediums on Goat Hair Follicles Cultured In Vitro

January 2008 in “ Journal of Shandong University ”

Zhang Zhao-yuan

hair follicles serum-free Williams E serum-free DMEM DMEM fetal calf serum vascular endothelial growth factor epidermal growth factor FCS VEGF EGF

TLDR Serum-free mediums with VEGF and EGF boost goat hair follicle growth best.

The study investigated the effects of different culture mediums on goat hair follicles in vitro, using a Jining Grey Goat's hair follicle. It compared serum-free Williams E, serum-free DMEM, and DMEM with 10% fetal calf serum (FCS), each with varying concentrations of vascular endothelial growth factor (VEGF) and epidermal growth factor (EGF). Results indicated that hair follicles grew well in all 9 tested mediums, but those in serum-free mediums exhibited faster growth than those in mediums with 10% serum. Additionally, the presence of VEGF and EGF significantly enhanced growth rates compared to mediums lacking these growth factors.

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