Low-Sulfur Hair Syndrome Associated with UVB Photosensitivity and Testicular Failure

    Paul A. Lucky, Neville Kirsch, Anne W. Lucky, D. Martin Carter
    TLDR Low-sulfur hair syndrome can cause UVB sensitivity and testicular failure.
    The document described a case of a 16-year-old male with a syndrome characterized by growth and mental retardation, hair shaft abnormalities, neurosensory hearing loss, contractures of the fifth fingers, UVB photosensitivity, small testicular size, and elevated follicle-stimulating hormone levels. The patient exhibited low-sulfur hair content and a unique pattern of birefringent bands in hair under polarization microscopy, typical of low-sulfur hair syndrome. Notably, UVB photosensitivity and testicular failure were newly identified components of this syndrome at the time.
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