Low Level Laser versus Platelet-rich Plasma in Treatment of Alopecia Areata: A Randomized Controlled Intra-patient Comparative Study

The study involved 30 patients with alopecia areata, each having three patches of hair loss. These patches were treated with either platelet-rich plasma (PRP) or low-level laser therapy (LLLT), or left untreated as a control. PRP was given once weekly, and LLLT three times per week for six weeks. The results showed significant improvement in hair thickness and density in the PRP-treated patches, as evaluated by the folliscope and patient satisfaction. These results were sustained during a 12-week follow-up period in most patients. The study concluded that both PRP and LLLT are effective treatments for alopecia areata, with minimal side effects and a favorable cost-benefit ratio.