TLDR Some family members had a condition with both loose hair and unique eye changes, possibly indicating a new type of ectodermal dysplasia.
The document detailed a study conducted 19 years ago on a family of 11 individuals with Loose Anagen Hair Syndrome (SCAF) and macular dystrophy. Two members had SCAF without any eye changes. Four members had eye changes, with two sisters having SCAF and pigmented dispersions in the back of the retina, along with macular coloboma. Two brothers had SCAF and pigmented dispersions in the back of the eye, but without coloboma. The study suggested that this combination of symptoms might represent a new classification within ectodermal dysplasias.
19 citations
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April 1995 in “Clinical Genetics” Two siblings were the first reported cases of inheriting both eye coloboma and loose anagen syndrome together.
55 citations
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October 1992 in “Archives of Dermatology” Loose Anagen Hair Syndrome is a hereditary condition causing hair loss in children due to abnormal hair follicles.
1 citations
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December 2017 in “JAMA Facial Plastic Surgery” Artificial hair implantation using scaffolds is possible and PHDPE is more biocompatible than ePTFE.
84 citations
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April 2002 in “Archives of Dermatology” Loose anagen hair syndrome may be caused by keratin gene mutations.
46 citations
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October 2009 in “Archives of Dermatology” Loose anagen hair syndrome, often affecting young girls, can be diagnosed with a hair-pull test and usually gets better on its own, but severe cases may need treatment.
40 citations
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January 2010 in “International Journal of Trichology” Loose Anagen Syndrome is a hair condition where hairs can be easily pulled out, mainly affecting young girls, and may improve on its own or with treatment.
31 citations
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December 2010 in “Journal of the American Academy of Dermatology” Loose anagen hair syndrome is caused by structural abnormalities in the hair follicle's inner root sheath.
