TLDR Some family members had a condition with both loose hair and unique eye changes, possibly indicating a new type of ectodermal dysplasia.
The document detailed a study conducted 19 years ago on a family of 11 individuals with Loose Anagen Hair Syndrome (SCAF) and macular dystrophy. Two members had SCAF without any eye changes. Four members had eye changes, with two sisters having SCAF and pigmented dispersions in the back of the retina, along with macular coloboma. Two brothers had SCAF and pigmented dispersions in the back of the eye, but without coloboma. The study suggested that this combination of symptoms might represent a new classification within ectodermal dysplasias.
19 citations
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April 1995 in “Clinical Genetics” Two siblings were the first reported cases of inheriting both eye coloboma and loose anagen syndrome together.
55 citations
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October 1992 in “Archives of Dermatology” Loose Anagen Hair Syndrome is a hereditary condition causing hair loss in children due to abnormal hair follicles.
A 14-year-old girl with Loose Anagen Hair Syndrome was successfully treated with oral Minoxidil and a Silicon supplement.
1 citations
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December 2017 in “JAMA Facial Plastic Surgery” Artificial hair implantation using scaffolds is possible and PHDPE is more biocompatible than ePTFE.
12 citations
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March 2018 in “Australasian Journal of Dermatology” Minoxidil treatment can reduce hair shedding, increase hair volume, and even change hair color in patients with loose anagen hair syndrome.
2 citations
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August 2012 in “Journal of the American Academy of Dermatology” Two patients with the same genetic mutation had both blistering skin and easily pulled out hair.
61 citations
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January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” Hair usually grows back 1-3 months after treatment for anagen effluvium, and children with Loose Anagen Hair Syndrome often improve by adolescence.
