Loose Anagen Hair Syndrome Associated with Macular Dystrophy: Description of a Family

December 2004 in “ Anais Brasileiros de Dermatologia ”

Mário Teruo Sato, Fabiane Mulinari Brenner, Rodrigo Marzagão, Fábio Sabbag, Gisele Bordignon, José Fillus Neto, Daura Regina Eiras-Stofella, Antônio Franco, Carlos Augusto Moreira Júnior

Loose Anagen Hair Syndrome SCAF macular dystrophy macular coloboma pigmented dispersions ectodermal dysplasias

TLDR Some family members had a condition with both loose hair and unique eye changes, possibly indicating a new type of ectodermal dysplasia.

The document detailed a study conducted 19 years ago on a family of 11 individuals with Loose Anagen Hair Syndrome (SCAF) and macular dystrophy. Two members had SCAF without any eye changes. Four members had eye changes, with two sisters having SCAF and pigmented dispersions in the back of the retina, along with macular coloboma. Two brothers had SCAF and pigmented dispersions in the back of the eye, but without coloboma. The study suggested that this combination of symptoms might represent a new classification within ectodermal dysplasias.

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Research cited in this study

2 / 2 results

research New Familial Association Between Ocular Coloboma and Loose Anagen Syndrome

19 citations, April 1995 in “Clinical Genetics”

Two siblings were the first reported cases of inheriting both eye coloboma and loose anagen syndrome together.

research Loose Anagen Hair as a Cause of Hereditary Hair Loss in Children

55 citations, October 1992 in “Archives of Dermatology”

Loose Anagen Hair Syndrome is a hereditary condition causing hair loss in children due to abnormal hair follicles.

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Loose Anagen Hair Syndrome Associated with Macular Dystrophy: Description of a Family

Research cited in this study

research New Familial Association Between Ocular Coloboma and Loose Anagen Syndrome

research Loose Anagen Hair as a Cause of Hereditary Hair Loss in Children

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