Long-Term Efficacy of Baricitinib in Alopecia Areata: 3-Year Results from BRAVE-AA1 and BRAVE-AA2

September 2024 in “ Journal of the American Academy of Dermatology ”

Maryanne M. Senna, Arash Mostaghimi, Manabu Ohyama, Rodney Sinclair, Chiara Chiasserini, Yves Dutronc, Najwa Somani, Guanglei Yu, Jill Kolodsick, Lucy Liu

baricitinib alopecia areata SALT score hair regrowth

TLDR Baricitinib maintains significant hair regrowth in severe alopecia areata over three years.

The study evaluates the long-term efficacy of baricitinib in treating severe alopecia areata over three years, focusing on patients who responded to treatment by Week 52 with a SALT score of ≤20. Results from the BRAVE-AA1 and BRAVE-AA2 trials show that 89.1% of patients on 4mg and 83.6% on 2mg maintained this level of scalp hair regrowth by Week 152. Additionally, significant improvements in eyebrow and eyelash regrowth were observed, with 80% and 66.7% of 4mg and 2mg patients, respectively, achieving notable eyebrow regrowth, and 80.9% and 78.1% achieving eyelash regrowth. These findings support the long-term use of baricitinib for maintaining hair regrowth in severe alopecia areata.

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community What are the odds baricitinib will get a topical otc version for androgenic alopecia?

in Research/Science 1 year ago

Baricitinib, approved for alopecia areata, might be considered for treating receding hairlines. The discussion is about the possibility of an over-the-counter topical version for androgenic alopecia.

community Lilly to seek first approval of an autoimmune drug for hair loss

in Research/Science 18 upvotes 3 years ago

Eli Lilly's drug baricitinib showed effectiveness in treating alopecia areata, with higher doses resulting in significant hair regrowth compared to placebo. The treatment is not for male pattern baldness.

community Anyone else taking Litfulo (ritlecitinib) to treat their alopecia?

in Treatment 5 upvotes 1 year ago

A user diagnosed with Alopecia Areata started using Litfulo (ritlecitinib), kenalog shots, and mometasone furoate 0.1%. They shaved their head and are seeking others' experiences with Litfulo.

community I am a dermatologist with a clinical interest in alopecia. AMA

in Will treatment work for me? 2 years ago

In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

community Olumiant active ingredient Baricitinib

in Research/Science 1 upvotes 2 years ago

The conversation is about someone inquiring if anyone has tried Olumiant or its active ingredient, Baricitinib, for hair loss, mentioning the cost and that they have ordered Baricitinib.

community Anyone heard of or have experience using baricitinib?

in Research/Science 1 upvotes 1 year ago

The conversation is about baricitinib, a medicine that can help with hair loss, and why it isn't more popular or widely discussed. No specific experiences with the treatment were shared.

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research Twenty Nail Dystrophy with Alopecia Areata in an Atopic Child

April 2019 in “International journal of research in dermatology”

A child with rough nails also had hair loss and allergies.