Association of Lichen Planopilaris with Seborrheic Dermatitis: A Retrospective Case-Control Study

    April 2016 in “ Journal of The American Academy of Dermatology ”
    Image of study
    TLDR People with lichen planopilaris often have seborrheic dermatitis, which can delay the diagnosis of lichen planopilaris.
    The retrospective case-control study conducted at the Cleveland Clinic investigated the prevalence of seborrheic dermatitis (SD) in patients with lichen planopilaris (LPP). The study reviewed medical records of 246 LPP patients evaluated between 2004 and 2015. It was found that 106 (43.1%) of the LPP patients had a diagnosis of SD. SD was often diagnosed before LPP, with an average of 7.8 months prior, and was associated with delays in LPP diagnosis. Patients with both SD and LPP experienced a longer time to diagnosis after initial evaluation for hair loss (mean delay of 7.6 months) compared to LPP patients without SD (2.3 months). Additionally, there was a higher prevalence of late-stage cicatricial alopecia and a higher rate of comorbid hyperandrogenism in SD/LPP patients. The study concluded that SD is a common comorbidity in LPP patients and is associated with diagnostic delays and a greater rate of progression to late-stage disease. Further research is needed to understand the mechanisms behind these associations.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 56 results

      community Losing Hair on Dutasteride? You might have LPP

      in Research/Science  94 upvotes 3 weeks ago
      Men with hair loss might have lichen planopilaris (LPP), which can mimic androgenetic alopecia, leading to misdiagnosis and ineffective treatment with finasteride or dutasteride. Proper diagnosis, including biopsies, is crucial to distinguish between androgenetic alopecia and conditions like LPP.
      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 7 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community scarring alopecia awareness in this community

      in Chat  33 upvotes 2 years ago
      Lichen Planopilaris (LPP), a form of permanent hair loss, which can be mistaken for seborrheic dermatitis and is characterized by scalp itching, burning, redness, and dandruff. Treatment options discussed include steroidal creams, finasteride, minoxidil, and RU58841.

      community Hair Loss & Lipids: Why you have sebderm, folliculitis, LPP, inflammation, etc...

      in Research/Science  130 upvotes 2 weeks ago
      Excess sebum rich in cholesterol and triglycerides can lead to hair loss through inflammation, with treatments like Ciclopirox shampoo, Benzoyl Peroxide shampoo, and Clindamycin gel recommended for managing conditions like seborrheic dermatitis and folliculitis. Pioglitazone is suggested for Lichen Planopilaris, while Omega-3s and reducing processed foods may improve sebum quality, though genetic factors play a significant role.

      community The Worst Hair Loss Condition You (MAY) have: LPP

      in Research/Science  43 upvotes 7 months ago
      Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

      community Anger and frustration as I finally learn my diagnosis.

      in Female  6 upvotes 1 year ago
      A young female diagnosed with Lichen planopilaris (LPP) experienced years of misdiagnosis and ineffective treatments, including a hair transplant and other procedures. She is considering litigation due to the misdiagnosis and has learned that LPP is chronic, hair loss can be stopped with ongoing medication, but lost hair cannot regrow.

    Similar Research

    5 / 1000+ results