Mechanisms and Clinical Applications of Laser and Light Technologies in Modern Dermatology

    September 2025 in “ Cuadernos de Educación y Desarrollo
    Ana Cristina de Oliveira de Andrade, Clara Martins da Gama Davi, Davit Willian Bailo, Angela Silveira, Maria Eduarda Schaparini Fonini, Isabella Fedalto Kieutika, Camila Lopes Dias Arroyo, Ana Luiza Fleury Calaça, Edson Rodrigues Neto, Tuany Caroline Bernardi
    TLDR Laser and light technologies are used in dermatology for skin treatments and improving outcomes.
    This study provides an integrative review of laser and light technologies in modern dermatology, analyzing their fundamental biophysical mechanisms and clinical applications over the past decade. Key mechanisms include selective photothermolysis, photoacoustic, photochemical effects, and controlled ablation, each targeting specific skin chromophores for various clinical purposes. Common applications are skin rejuvenation, acne scar treatment, pigmentary disorders, vascular lesions, and permanent hair removal. Photobiomodulation with LEDs shows promise for androgenetic alopecia, inflammatory processes, and wound healing, while photodynamic therapy is effective for actinic keratoses and superficial basal cell carcinoma. The study highlights a trend towards combining technologies and personalizing protocols, often with artificial intelligence, to enhance efficacy and safety across different skin types. Understanding these mechanisms and standardizing clinical parameters are crucial for optimizing outcomes and developing consistent clinical guidelines.
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