Laser-Assisted Drug Delivery: A Systematic Review of Safety and Adverse Events

The systematic review on laser-assisted drug delivery (LADD) evaluates its safety and adverse events across various dermatological conditions, including hair loss. The review analyzed 70 articles and found that common adverse effects were generally mild, such as erythema, oedema, pain, and crusting, with more severe effects like dyspigmentation and scarring being rare. No life-threatening adverse effects were reported. The review highlights the potential of LADD as an alternative treatment for conditions like alopecia areata, though the limited number of studies and small sample sizes restrict the robustness of these findings. It emphasizes the need for more rigorous studies to better understand the safety profile of LADD, as current data often lack detailed adverse effect characterization and long-term follow-up.