Geochemistry and Human Selenium Imbalances in China

    October 1997
    F.M. Fordyce, Geli ZHANG, C.C. Johnson, Xiaoli Ge, J.D. Appleton, Q. Zhang, X. Lui, Jiashuai Li
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    Studysummary This review discusses the link between selenium levels in the environment and related diseases in China, reporting no clinical results; the authors highlight the need for clearer geographic risk and remediation strategies.
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    The document discussed the role of selenium (Se) in human health in China, highlighting its necessity in small doses and toxicity in excess. It noted that China had extensive epidemiological data linking Se deficiency to diseases like Keshan Disease, Kashin-Beck Disease, and oesophageal cancer, while excess Se caused hair loss and nail deformation. Despite this, the specific geographic areas at risk and the geochemical factors affecting Se levels were not well-defined, and effective remediation strategies had not been established.
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