Iron and Skin Health: Iron Stimulates Skin Function

The document discussed the role of iron, specifically Fe (II) and Fe (III) dimers like ferrous ferric chloride, in skin health and function. It highlighted that while iron is essential for the development of skin and its appendages, the mechanisms of iron uptake and regulation in the skin were not well understood. The study found that normal iron levels were crucial for maintaining healthy skin, hair, and nails, and that ferrous ferric chloride played a significant role in regulating skin cell proliferation and differentiation. It was noted that ferrous ferric chloride could stimulate these processes even without direct addition to the culture medium, suggesting its involvement in skin homeostasis and cell turnover regulation.