Influence of Postoperative Finasteride Therapy on Recurrence of Gynecomastia After Mastectomy in Men Taking Finasteride for Alopecia

    September 2019 in “American Journal of Men's Health
    Seunggeun Lee, Pyoung-Jae Park, Sung Koo Lee, Bum Hwan Koo, Geon Young Byun, Myoung-Jin Kim, Hyok Kang, Sarang Kim, Beom-Seok Oh, Younghyun Lee
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    TLDR Finasteride may not affect gynecomastia recurrence after mastectomy.
    This study investigated whether finasteride should be continued after mastectomy when gynecomastia occurs in patients taking finasteride for alopecia. The study included 52 patients taking finasteride for alopecia before mastectomy, and the median duration of finasteride therapy before and after surgery was 12 and 33 months, respectively. The study found that there were no statistically significant differences between the groups with and without the use of finasteride with respect to postoperative complications and recurrence rates. No recurrence was noted during the follow-up period in the group of patients taking finasteride. The study concluded that after complete excision of the mammary gland, finasteride treatment might not affect the recurrence of gynecomastia, but additional prospective studies are needed. Surgeons may recommend continuation of finasteride in patients who wish to take it after mastectomy for gynecomastia.
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