Hyperactivation of sympathetic nerves drives depletion of melanocyte stem cells

January 2020 in “ Nature ”

Bing Zhang, Sai Ma, Inbal Rachmin, Megan He, Pankaj Baral, Sekyu Choi, William Antônio Gonçalves, Yulia Shwartz, Eva M. Fast, Yiqun Su, Leonard I. Zon, Aviv Regev, Jason D. Buenrostro, Thiago M. Cunha, Isaac M. Chiu, David E. Fisher, Ya‐Chieh Hsu

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Research cited in this study

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research External Light Activates Hair Follicle Stem Cells Through Eyes Via an ipRGC–SCN–Sympathetic Neural Pathway

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research EdnrB Governs Regenerative Response of Melanocyte Stem Cells by Crosstalk with Wnt Signaling

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research Emerging Interactions Between Skin Stem Cells and Their Niches

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research Coordinated Activation of Wnt in Epithelial and Melanocyte Stem Cells Initiates Pigmented Hair Regeneration

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Wnt signaling is crucial for pigmented hair regeneration by controlling stem cell activation and differentiation.

research Marie Antoinette Syndrome

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Marie Antoinette syndrome causes sudden hair whitening, but its exact cause is unknown.

research Melanocyte Stem Cell Maintenance and Hair Graying

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Hair graying happens because certain cells aren't maintained properly.