Individual Human Hair Keratin Extracted Through Advanced Oxidation Process and Hemostatic and Wound Healing Evaluations
November 2023
in “
ACS Applied Polymer Materials
”
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Studysummary In this study, the researchers developed a new method using H2O2/TiO2/UV for extracting human hair keratins rapidly, yielding higher protein and enabling the production of keratin films with better hemostatic performance and varied wound-healing properties compared to films from traditionally extracted keratin.
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The document presents a new method for extracting keratin from human hair using a TiO2 photocatalytic-assisted H2O2 oxidation strategy (H2O2/TiO2/UV), which is faster and yields more protein than the traditional H2O2 method. The keratin extracted using this method retains its typical chemical and secondary structures. The study also fabricated individual keratin/PCL films from the keratin of four young girls, which showed superior hemostatic performance and wound healing in vivo compared to keratin extracted via the H2O2 method. Interestingly, while the hemostatic efficiency was similar across all four keratin films, they displayed distinct wound-healing properties in terms of epidermal thickness and density of skin appendages. This suggests the potential for personalized wound healing materials.
