High-Performance Liquid Chromatographic Determination of Finasteride in Human Plasma Using Direct Injection with Column Switching

February 1996 in “ Journal of Chromatography B: Biomedical Sciences and Applications ”

Terukazu Takano, Shunsuke Hata

finasteride high-performance liquid chromatography HPLC human plasma Propecia

TLDR New method detects finasteride in plasma quickly and accurately without clean-up.

The paper presents a new automated HPLC method for detecting finasteride in human plasma without clean-up. The method is sensitive and accurate, allowing for the analysis of more than 30 plasma samples per day without an internal standard. It is suitable for use in clinical studies.

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research Picogram Determination of Finasteride in Human Plasma and Semen by High-Performance Liquid Chromatography with Atmospheric-Pressure Chemical-Ionization Tandem Mass Spectrometry

45 citations , August 1994 in “Journal of Chromatography B: Biomedical Sciences and Applications”

Method detects finasteride in plasma and semen with high sensitivity and accuracy.

research High-performance liquid chromatographic method for the determination of finasteride in human plasma at therapeutic doses

19 citations , May 1991 in “Journal of Chromatography B: Biomedical Sciences and Applications”

Reliable method detects finasteride in human plasma at low doses.

research Species Differences in Prostatic Steroid 5α-Reductases of Rat, Dog, and Human

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Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.