Hair Restoration

January 2012 in “ Springer eBooks ”

Samuel M. Lam

hair restoration follicular hair transplantation hair loss hair replacement patterns of baldness

TLDR Hair restoration has greatly improved since 1992, moving from obvious grafts to unnoticeable hair transplants, thanks to better knowledge and dedication to excellence.

In 2012, the field of hair restoration had significantly evolved over the previous two decades, transitioning from noticeable plug grafts to undetectable follicular hair transplantation. This advancement was based on a better understanding of hair loss and hair replacement, patterns of baldness, anesthesia, and techniques. The improvement in hair restoration was largely due to substantial experience, artistry, and a commitment and passion for excellence without compromise.

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Research cited in this study

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research Finasteride Treatment of Female Pattern Hair Loss

108 citations, March 2006 in “Archives of Dermatology”

Finasteride with oral contraceptive helps improve hair loss in premenopausal women.

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18 citations, July 2003 in “Dermatologic Surgery”

The conclusion is that creating natural-looking hair restoration requires replicating natural scalp whorl patterns and inserting grafts at specific angles.

research Female Pattern Hair Loss

226 citations, September 2001 in “Journal of The American Academy of Dermatology”

Hair loss in women is genetic, diagnosed by examination and biopsy, and treated with minoxidil, finasteride, or transplantation.

research Lack of Efficacy of Finasteride in Postmenopausal Women with Androgenetic Alopecia

239 citations, November 2000 in “Journal of The American Academy of Dermatology”

Finasteride doesn't effectively treat hair loss in postmenopausal women.

research Finasteride in the Treatment of Men with Androgenetic Alopecia

581 citations, October 1998 in “Journal of The American Academy of Dermatology”

Finasteride safely and effectively treats male pattern hair loss, but may cause reversible sexual issues and harm male fetuses.

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Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

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Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.

community COMPLETE OVERVIEW of the Treatment of androgenetic alopecia in men

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Male androgenetic alopecia is commonly treated with topical minoxidil and oral finasteride, both requiring continuous use. Other options include hair restoration surgery, dutasteride, light therapy, and camouflaging agents.

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Modern hair restoration techniques can effectively treat hair loss and provide natural-looking results.

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