Diffuse Hair Loss in Addison Disease: A Reason for X-Linked Adrenoleukodystrophy Screening

    April 2012 in “ Journal of the American Academy of Dermatology ”
    Beatriz Lecumberri, M. Girós, María Josep Coll, Amparo Marco, Mariano Casado, Luís Felipe Pallardo, Javier Pardo
    TLDR Men with Addison disease should be screened for X-linked adrenoleukodystrophy if they have hair loss.
    A 28-year-old man with Addison disease (AD) since age 14 experienced diffuse hair loss and neurological symptoms, leading to a diagnosis of X-linked adrenoleukodystrophy (ALD) due to a mutation in the ABCD1 gene. This case highlighted the importance of screening for ALD in adult men with AD, especially those without circulating antiadrenal cortex antibodies, as hair loss might be misattributed to AD or corticosteroid therapy, delaying correct diagnosis. The patient showed partial symptom relief with baclofen and lovastatin, and his condition remained stable over three years.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 1000+ results
      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      by nkrata in Research  830 upvotes 1 year ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Being realistic with expectations

      in Finasteride/Dutasteride  6 upvotes 4 years ago
      User tried finasteride, minoxidil, redensyl solution, PRP sessions, essential oils, diet, exercise, and microneedling for hair loss. Experienced slight regrowth, reduced hair fall, and stopped hairline receding; advises realistic expectations and considering regrowth as a bonus.

      community Hypertrichosis Photos from Oral Minoxidil

      in Progress Pictures  266 upvotes 2 years ago
      A user shared their experience with oral minoxidil and finasteride for hair loss, taking 7.5mg of minoxidil and experiencing excessive hair growth all over their body without major side effects. Some users suggested lower doses for safety, while others shared their own experiences with hair growth in different areas and side effects.

      community Couldn’t be more happy! 5 Months Fin and Min, 19M

      in Progress Pictures  346 upvotes 2 years ago
      A 19-year-old man is happy with his hair regrowth after 5 months of using finasteride and minoxidil, and he also found a supportive girlfriend while dealing with hair loss and acne. He emphasizes patience and taking progress photos for those struggling with similar issues.

    Similar Research

    5 / 1000+ results