Changes in Hair: Causative Factors

January 1996

Masumi Inaba, Yoshikata Inaba

dihydrotestosterone DHT testosterone glucose-6-phosphate-dehydrogenase G6PDH cyclic adenosine monophosphate AMP anagen phase alopecia androgen levels 5α-DHT matrix cells hair follicles hirsutism sebaceous gland acne

TLDR DHT, not testosterone, mainly affects hair growth and related conditions.

The document discussed the hormonal control of hair growth, focusing on the role of dihydrotestosterone (DHT) as the active form of testosterone in hair follicles. It highlighted that glucose-6-phosphate-dehydrogenase (G6PDH) activity, stimulated by cyclic adenosine monophosphate (AMP), increased significantly during the anagen phase of hair growth. The study noted a correlation between alopecia progression and declining androgen levels, emphasizing that 5α-DHT, rather than testosterone, stimulated matrix cells in hair follicles, particularly in women with hirsutism. This mechanism was also relevant to sebaceous gland activity in acne.

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community Saying creatine causes loss on fin/dut makes no sense and this is why

in Finasteride/Dutasteride 42 upvotes 1 year ago

The conversation discusses whether creatine causes hair loss for those using finasteride or dutasteride, with some suggesting creatine might increase DHT or upregulate androgen receptors, potentially leading to hair loss. Others argue the evidence is not conclusive, citing limited studies and personal anecdotes, with some avoiding creatine as a precaution.

community Creatine and Finasteride together - still started losing hair

in Finasteride/Dutasteride 20 upvotes 2 years ago

User experienced hair loss after taking creatine with finasteride for 8 years. Others shared similar experiences, but some suggested it could be a minoxidil shed.

community Does whey protein and creatine aggravate hair loss?

in Research/Science 81 upvotes 2 years ago

The conversation discusses whether whey protein and creatine worsen hair loss. Some users report hair loss with creatine use, while others do not; opinions on whey protein's effects are mixed. Treatments mentioned include PRP, minoxidil, and finasteride.

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 1 year ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

in Research 865 upvotes 1 year ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community What should I include in my blood test?

in Treatment 1 upvotes 2 months ago

The user has been using finasteride, dutasteride, and minoxidil without success and is considering a comprehensive blood test to explore other causes of hair loss. They are unsure about the necessity and cost of the extensive tests and are seeking advice on whether to proceed with the full panel or focus on specific tests.

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Morphogenesis, Growth Cycle, and Molecular Regulation of Hair Follicles

Changes in Hair: Causative Factors

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community Saying creatine causes loss on fin/dut makes no sense and this is why

community Creatine and Finasteride together - still started losing hair

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community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

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