Formulation and Evaluation of PLGA Nanoparticulate-Based Microneedle System for Potential Treatment of Neurological Diseases

July 2023 in “ International Journal of Nanomedicine ”

Baohua Li, Lu Geng, Wenbin Liu, Liqi Liao, Junfeng Ban, Zhufen Lu

The study explores the use of PLGA nanoparticulate-based microneedle systems as a potential treatment for neurological diseases. Nanoparticles are highlighted for their ability to extend blood circulation and intracerebral retention times, as well as their brain-targeting properties. By combining microneedle technology with nanocarriers, the research suggests a promising new delivery system for central neurological disease treatment. This innovative approach aims to enhance the effectiveness and precision of drug delivery to the brain.

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