Action of Finasteride on Prostate Volume in Dogs with Benign Prostatic Hyperplasia

January 2002 in “ El Servicio de Difusión de la Creación Intelectual (National University of La Plata) ”

María Alejandra Stornelli, María Cecilia Stornelli, Raúl Ricardo Rodríguez, Carla Floriana Scodellaro, César A. Savignone

finasteride 5 alpha-reductase inhibitor benign prostatic hyperplasia Propecia

TLDR Finasteride effectively reduces prostate size in dogs with benign prostatic hyperplasia at a low, safe dose.

In this study, adult male dogs with varying degrees of benign prostatic hyperplasia were administered 0.1 mg/kg per day of Finasteride, a selective 5 α-reductase inhibitor, orally. The treatment significantly reduced prostate size as evaluated by ultrasound, without any associated toxic side effects. Notably, the dosage used was 10 times lower than that used in other studies, yet it achieved similar results. This lower dosage reduced treatment costs and maintained safety, suggesting that Finasteride could be an excellent long-term treatment option for benign prostatic hyperplasia.

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in Research 330 upvotes 1 year ago

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in Chat 1 upvotes 1 month ago

Saw palmetto, a 5-alpha reductase inhibitor, caused unexpected side effects like breast changes and altered semen consistency, which resolved after stopping its use. Concerns about similar side effects with finasteride or dutasteride were expressed, and another user reported low libido and depression from saw palmetto.

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