Efficacy of Platelet-Rich Plasma in the Treatment of Thin Endometrium: A Meta-Analysis of Randomized Controlled Trials

This meta-analysis evaluated the efficacy of intrauterine autologous platelet-rich plasma (PRP) infusion in treating thin endometrium by analyzing 8 randomized controlled trials with 678 patients. PRP infusion significantly improved endometrial thickness, clinical pregnancy rate, live birth rate, cycle cancellation rate, and embryo implantation rate compared to the control group. However, there were no significant differences in spontaneous abortion rate, chemical pregnancy rate, and endometrial vascular improvement rate. Despite promising results, limitations such as language restriction, sample size, and heterogeneity suggest the need for further high-quality, large-sample trials to confirm these findings.