Efficacy of Photobiomodulation Versus Its Combination with Plasma Rich Growth Factors or Minoxidil in Management of Androgenetic Alopecia

April 2022 in “ Zenodo (CERN European Organization for Nuclear Research) ”

MohammedI Eitta, Ahmed Kamel Sadek, Noha N. Amer, Nevien Samy, Noha Abdallah

photobiomodulation plasma rich growth factors Minoxidil androgenetic alopecia low-level light therapy platelet-rich plasma folliscopic analysis PRGFs LLLT PRP Rogaine AGA

TLDR Combining PRP with LLLT is most effective for hair growth in androgenetic alopecia.

The study evaluated the effectiveness of low-level light therapy (LLLT) alone and in combination with plasma rich growth factors (PRGFs) or Minoxidil in managing androgenetic alopecia (AGA) in 45 patients. The patients were divided into three groups: LLLT with PRP, LLLT with Minoxidil, and LLLT alone, and treated for 3 months with a follow-up after 3 months. Results showed that the combination of PRP with LLLT led to the most significant improvement in hair growth, as evidenced by global photography, folliscopic analysis, and patient satisfaction, compared to the other treatments. Thus, PRP combined with LLLT was concluded to be more effective than LLLT with Minoxidil or LLLT alone for AGA management.