Evaluating the Efficacy of Negative Pressure Wound Therapy in Reducing Surgical Site Infections: A Systematic Review

This systematic review assessed the efficacy of Negative Pressure Wound Therapy (NPWT) in reducing surgical site infections (SSIs) and improving wound care outcomes. The review included 8 high-quality randomized controlled trials with 1,196 patients, focusing on conditions like diabetic foot ulcers and post-arthroplasty wounds. NPWT was compared to traditional dressings, showing significant improvements in reducing infection rates and accelerating wound healing (p < 0.05). The therapy also promoted epithelialization and reduced complications such as blister formation and seromas. While NPWT shows promise, further research is needed to confirm its effectiveness in dermatology-specific surgical contexts.