Effectiveness of Combined Topical Ethinylestradiol and Minoxidil Versus Minoxidil Alone in Treating Female Pattern Hair Loss

This study investigated the effectiveness and safety of a combination therapy of topical ethinylestradiol 0.01% and minoxidil 2% compared to minoxidil 2% alone in treating female pattern hair loss. Conducted on 43 female patients aged 18 to 55 with Ludwig grade I-II-III hair loss, the trial divided participants into two groups: one using the combination therapy and the other using only minoxidil. After 24 weeks, both treatments were found to be almost equally effective in promoting hair growth. However, the minoxidil-only treatment was superior in terms of tolerability, with fewer side effects reported.