Effectiveness and safety of oral dutasteride for male androgenetic alopecia in real clinical practice: A descriptive monocentric study
January 2020
in “Dermatologic Therapy”
TLDR Oral dutasteride improves hair growth, reduces hair loss, and is safe for most patients.
This document is a compilation of studies that examined the effectiveness and safety of oral dutasteride for male androgenetic alopecia in real clinical practice. The studies involved a total of 524 male patients and found that oral dutasteride was effective in improving hair growth and reducing hair loss in the majority of patients, with minimal adverse effects. Low doses of oral dutasteride were found to be effective and well-tolerated, and intermittent use of the drug was also found to be effective due to its long half-life. The studies suggest that oral dutasteride can be a safe and effective treatment option for male androgenetic alopecia in real clinical practice.
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Cited in this study
research Estudio transversal acerca de los hábitos de prescripción en alopecia androgénica de los dermatólogos en España en 2017
In 2017, Spanish dermatologists most often prescribed minoxidil and finasteride for male hair loss, and minoxidil and oral contraceptives for premenopausal female hair loss.
research Evidence-based (S3) guideline for the treatment of androgenetic alopecia in women and in men – short version
Use minoxidil for hair loss treatment; assess results after 6 months.
research Long-term efficacy and safety of the dual 5-alpha reductase blocker dutasteride on male androgenetic alopecia patients
Dutasteride effectively and safely treats male hair loss for over a year.
research Superiority of dutasteride over finasteride in hair regrowth and reversal of miniaturization in men with androgenetic alopecia: A randomized controlled open-label, evaluator-blinded study
Dutasteride is more effective than finasteride at increasing hair count and reversing hair thinning in men with hair loss, but both have similar side effects.
research A randomized, active- and placebo-controlled study of the efficacy and safety of different doses of dutasteride versus placebo and finasteride in the treatment of male subjects with androgenetic alopecia
Dutasteride 0.5 mg works better than finasteride and placebo for increasing hair in men with hair loss.
research The importance of dual 5α-reductase inhibition in the treatment of male pattern hair loss: Results of a randomized placebo-controlled study of dutasteride versus finasteride
Dutasteride more effective for hair growth, but has more side effects than finasteride.
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research Long-term safety and efficacy of dutasteride in the treatment of male patients with androgenetic alopecia
Dutasteride safely promotes hair growth and reduces hair loss, with mild side effects.
research Adverse Side Effects of 5α‐Reductase Inhibitors Therapy: Persistent Diminished Libido and Erectile Dysfunction and Depression in a Subset of Patients
Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.