Diagnostic Approach to Acute Disseminated Encephalomyelitis
February 2025
in “
Cermin Dunia Kedokteran
”
TLDR ADEM is a sudden brain disorder often following infection or vaccination, diagnosed by ruling out other conditions.
Acute disseminated encephalomyelitis (ADEM) is an acute neurological disorder characterized by demyelination of the central nervous system. It can affect all age groups but is more common in boys with a history of exposure to viral or bacterial infections or vaccination. The disease typically presents acutely and is monophasic, with multifocal neurological deficits. ADEM lacks specific symptoms, as clinical manifestations depend on the location of demyelination. There are no specific tests for ADEM, so diagnosis is made by exclusion.