The Diagnostic Algorithm in Pre-Invasive Cervical Lesions

The document discussed the importance of screening for pre-invasive cervical lesions, which significantly decreased cervical neoplasm incidence. Screening was recommended to start at age 21, every 3-5 years, using pap smear testing and HPV genotyping, with follow-up procedures like colposcopy or biopsy if needed. Most intraepithelial lesions were linked to HPV, with other factors like immunosuppression and multiparity also contributing. HPV vaccination, recommended for ages 11-26 and older with risk factors, helped reduce recurrence rates in CIN2 patients. Studies showed HPV infections could be transient, with lesions sometimes regressing spontaneously. Early diagnosis was crucial for timely treatment and reducing cervical cancer incidence, facilitated by national health programs.