Dermatological Concerns for Women and Girls with Turner Syndrome

The study on dermatological concerns in women and girls with Turner Syndrome (TS) involved 241 participants and revealed a high prevalence of skin conditions such as dry skin (78.7%), increased acquired melanocytic nevi (71.2%), and alopecia areata (3-7%). It also found higher rates of lymphedema (33.0%), hair thinning (37.6%), onychodystrophy (44%), and keloids (40.9%) compared to the general population. These conditions significantly impact quality of life, with xerosis cutis having the strongest negative effect. Despite these prevalent issues, there is a lack of clinical guidelines for dermatological care in TS, and many individuals do not receive treatment due to infrequent referrals to dermatologists. The study emphasizes the need for better dermatological surveillance, routine care, and specialized referrals to improve the quality of life for individuals with TS.